Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367137 | 1.00 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BNPC1RAB9A | |
| SCHEMBL7367134 | 1.00 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BNPC1RAB9A | |
| SCHEMBL7376626 | 0.88 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7376623 | 0.88 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7375232 | 0.88 | POLB (0.40) | AVPR2NPC1RAB9A | |
| SCHEMBL7375748 | 0.88 | POLB (0.40) | AVPR2NPC1RAB9A | |
| SCHEMBL7375229 | 0.88 | POLB (0.40) | AVPR2NPC1RAB9A | |
| SCHEMBL7377221 | 0.88 | PPARD (0.45) | AVPR2 | |
| SCHEMBL7377226 | 0.88 | PPARD (0.45) | AVPR2 | |
| SCHEMBL7369639 | 0.87 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |