Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369642 | 1.00 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7370995 | 0.88 | AVPR2 (0.48) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7372097 | 0.88 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7372942 | 0.87 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7367137 | 0.87 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7751053 | 0.87 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7748312 | 0.87 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7367134 | 0.87 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7377178 | 0.85 | RECQL (0.45) | AVPR2GAA | |
| SCHEMBL7375061 | 0.84 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |