Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750800 | 0.90 | KDM4E (0.44) | TSHRRECQLALDH1A1EGFRKDM4E | |
| SCHEMBL7750875 | 0.90 | TSHR (0.42) | TSHRRECQLALDH1A1EGFRKDM4E | |
| SCHEMBL7749116 | 0.90 | NR5A1 (0.46) | ALDH1A1HPGDNR5A1 | |
| SCHEMBL7743661 | 0.87 | TSHR (0.42) | TSHRRECQLALDH1A1EGFRKDM4E | |
| SCHEMBL7750917 | 0.86 | NR5A1 (0.47) | TSHRRECQLMEN1KMT2ANR5A1 | |
| SCHEMBL7750807 | 0.85 | CNR2 (0.52) | NR5A1 | |
| SCHEMBL7195903 | 0.85 | TSHR (0.63) | TSHRRECQLALDH1A1EGFRKDM4E | |
| SCHEMBL7195953 | 0.85 | TSHR (0.63) | TSHRRECQLALDH1A1EGFRKDM4E | |
| SCHEMBL7750960 | 0.83 | NR5A1 (0.48) | TSHRMEN1KMT2ANR5A1 | |
| SCHEMBL7747879 | 0.83 | TSHR (0.47) | TSHRRECQLALDH1A1EGFRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184180-B1 | COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-02-06 | — | — | US | disclosed |