Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750875 | 0.94 | TSHR (0.42) | KDM4ETSHRRECQLNR5A1ALDH1A1 | |
| SCHEMBL7748398 | 0.90 | TSHR (0.48) | KDM4ETSHRRECQLNR5A1ALDH1A1 | |
| SCHEMBL7749255 | 0.85 | NR5A1 (0.43) | NR5A1MEN1KMT2ALTA4H | |
| SCHEMBL7197998 | 0.84 | KDM4E (0.55) | KDM4ETSHRRECQLNR5A1ALDH1A1 | |
| SCHEMBL7200734 | 0.84 | KDM4E (0.55) | KDM4ETSHRRECQLNR5A1ALDH1A1 | |
| SCHEMBL7750917 | 0.84 | NR5A1 (0.47) | TSHRRECQLNR5A1MEN1KMT2A | |
| SCHEMBL7749108 | 0.84 | KDM4E (0.45) | KDM4ETSHRRECQLNR5A1ALDH1A1 | |
| SCHEMBL7750898 | 0.84 | NR5A1 (0.45) | NR5A1LTA4H | |
| SCHEMBL7750807 | 0.84 | CNR2 (0.52) | NR5A1 | |
| SCHEMBL7750784 | 0.84 | NR5A1 (0.42) | NR5A1MAPTSMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184180-B1 | COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-02-06 | — | — | US | disclosed |