Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621673 | 0.97 | — | — | |
| Water SCHEMBL2152723 | 0.97 | — | — | |
| SCHEMBL15222 | 0.97 | — | — | |
| SCHEMBL7533725 | 0.97 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9517518 | 0.94 | — | — | |
| SCHEMBL8342097 | 0.94 | — | — | |
| SCHEMBL8489236 | 0.94 | — | — | |
| Hydrogen Sulfide SCHEMBL22127086 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL2152574 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL2800692 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180171112-A1 | ANTICORROSIVE FLAME RETARDANT FORMULATIONS FOR THERMOPLASTIC POLYMERS | CLARIANT PLASTICS & COATINGS LTD (CH) | 2018-06-21 | — | — | US | claimed |
| EP-1456286-B1 | EXPANDABLE EPOXY RESIN-BASED SYSTEMS MODIFIED WITH THERMOPLASTIC POLYMERS | HENKEL AG & CO KGAA (DE) | 2012-06-13 | — | — | EP | claimed |
| WO-2001009392-A1 | LEATHER TANNING | RHODIA CONSUMER SPECIALTIES LIMITED (GB) | 2001-02-08 | — | — | WO | claimed |
| EP-0388816-B1 | PASSIVATION OF PYROPHORIC METALS | SKW Trostberg Aktiengesellschaft (DE) | 1992-01-22 | — | — | EP | claimed |
| EP-0388816-A1 | Passivation of pyrophoric metals | SKW Trostberg Aktiengesellschaft (DE) | 1990-09-26 | — | — | EP | claimed |
| CN-111747895-A | Performance-adjustable self-combustion type multi-ionic liquid | 天津大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-107474246-B | One-pot method for preparing biguanide polymer | 武汉桀升生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-109640656-A | The synergistic combination of biocide | 伦萨公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108431238-A | Method for preserving skin or skin | 阿切化学巴西有限公司 | 2018-08-21 | — | — | CN | disclosed |
| EP-0878213-B1 | Fire extinguishing composition employing a eutectic salt mixture and water and method of using the same | ANSUL INC (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-0878213-A2 | A combination of a novel fire extinguishing composition employing a eutectic salt mixture and water and a method using same to extinguish fires | ANSUL, INCORPORATED (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5820776-A | UNIQUE MIXTURE OF ATLEAST TWO SALTS, FIRST CONTAINS CARBONATES OR BICARBONATE SALTS OF SODIUM OR POTASSIUM, SECOND SALT IS SELECTED FROM CHLORIDE, SULFATE, CITRATE OR TARTRATE OF SODIUM AND POTASSIUM COMBINED WITH WATER | ANSUL, INCORPORATED (US) | 1998-10-13 | — | — | US | disclosed |
| US-4913705-A | COLORFASTNESS, LEVEL DYEINGS | SANDOZ LTD. (CH) | 1990-04-03 | — | — | US | disclosed |
| US-4670017-A | MIXTURE WITH REACTION PRODUCT OF AMINE WITH CYANAMIDE, DICYANDIAMIDE, BIGUANIDINE, AND METHYLOL DERIVATIVE OF UREA TYPE COMPOUND OR EPICHLORHYDRIN | SANDOZ LTD. (CH) | 1987-06-02 | — | — | US | disclosed |