Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748785 | 1.00 | KMT2A (0.51) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL6743212 | 0.84 | KMT2A (0.51) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL6743215 | 0.84 | KMT2A (0.51) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL16993727 | 0.83 | MAPT (0.43) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL16993729 | 0.83 | MAPT (0.43) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL6573496 | 0.83 | KMT2A (0.44) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5702944 | 0.82 | RAB9A (0.42) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5702947 | 0.82 | RAB9A (0.42) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7266202 | 0.81 | KMT2A (0.43) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL7747561 | 0.81 | MEN1 (0.66) | KMT2AMEN1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |