Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748805 | 1.00 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL7748691 | 0.87 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL7748687 | 0.87 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL1157540 | 0.86 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL1157544 | 0.86 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL1157542 | 0.86 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL7750354 | 0.85 | MAPT (0.56) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL7750350 | 0.85 | MAPT (0.56) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| Water SCHEMBL6574634 | 0.84 | MAPT (0.55) | MEN1KMT2ASMN1; SMN2PSMD14HPGD | |
| SCHEMBL17044522 | 0.84 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2PSMD14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |