Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157540 | 1.00 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL13673630 | 0.90 | GUSB (0.47) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL13673628 | 0.90 | GUSB (0.47) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL915422 | 0.87 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL915421 | 0.87 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL13673673 | 0.86 | MAPT (0.55) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL7748807 | 0.86 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL7748805 | 0.86 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL13673676 | 0.86 | MAPT (0.55) | MEN1KMT2ASMN1; SMN2BLMPSMD14 | |
| SCHEMBL13673688 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2BLMPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410174-B2 | Method for treating arthritis | ANAMAR AB (SE) | 2013-04-02 | — | — | US | disclosed |
| US-8309609-B2 | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands | ANAMAR AB (SE) | 2012-11-13 | — | — | US | disclosed |
| US-20120190751-A1 | COMPOUNDS FOR TREATMENTS OF INFLAMMATION | ANA-MAR AB (SE) | 2012-07-26 | — | — | US | disclosed |
| EP-2470270-A1 | COMPOUNDS FOR TREATMENT OF INFLAMMATION | AnaMar AB (SE) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011012868-A1 | COMPOUNDS FOR TREATMENT OF INFLAMMATION | ANAMAR AB (SE) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190751-A1 | COMPOUNDS FOR TREATMENTS OF INFLAMMATION | IL6, IL1B, TNF | MEN1 4612/4885KMT2A 1259/4885SMN1; SMN2 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.