Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012149 | 0.74 | MEN1 (0.53) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL29391624 | 0.73 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL221242 | 0.73 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL30947359 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL6175584 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL6574416 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL11133606 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR | |
| Bromide SCHEMBL28368455 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL4243882 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR | |
| SCHEMBL6175579 | 0.71 | KMT2A (0.73) | MEN1KMT2AMAPK10GFERKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022965-A1 | SUBSTITUTED IMIDAZOLES HAVING CYTOKINE INHIBITORY ACTIVITY | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |