Ethyl Bromo Acetate

Ethyl Bromo Acetate

SCHEMBL7748940

CCOC(=O)CBr.CCSCC

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.77
TRPA1 O75762 1/20 0.77
GAA P10253 3/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
CYP2C19 P33261 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 1/20 0.37
SOAT1 P35610 1/20 0.37
GSK3A P49840 1/20 0.34
GSK3B P49841 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0776201-B1 Treating anxiety LILLY CO ELI (US) 2001-10-17 EP disclosed
EP-0776200-A4 COMPOSITION AND METHOD FOR PROTECTION AGAINST DRUG DEPENDENCY LILLY CO ELI (US) 2001-01-17 EP disclosed
EP-0776201-A4 COMPOSITION AND METHOD FOR TREATING ANXIETY LILLY CO ELI (US) 1999-07-07 EP disclosed
US-5882671-A USING AN AGONIST WHICH ACTS AT NEGATIVELY COUPLED CAMP-LINKED METABOTROPIC GLUTAMATE RECEPTORS ELI LILLY AND COMPANY (US) 1999-03-16 US disclosed
US-5661184-A ADMINISTERING AN AGONIST TO TREAT BENZODIAZEPINE DRUG ABUSE, DRUG DEPENDENCE ELI LILLY AND COMPANY (US) 1997-08-26 US disclosed
EP-0776200-A1 COMPOSITION AND METHOD FOR PROTECTION AGAINST DRUG DEPENDENCY ELI LILLY AND COMPANY (US) 1997-06-04 EP disclosed
EP-0776201-A1 COMPOSITION AND METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1997-06-04 EP disclosed
WO-1996004901-A1 COMPOSITION AND METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-02-22 WO disclosed
WO-1996004900-A1 COMPOSITION AND METHOD FOR PROTECTION AGAINST DRUG DEPENDENCY ELI LILLY AND COMPANY (US) 1996-02-22 WO disclosed