Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749078 | 1.00 | GBA1 (0.70) | GBA1TSHRSLC2A1TNFAKT1 | |
| SCHEMBL14000856 | 0.88 | GBA1 (0.52) | GBA1TSHRSLC2A1TNFBCHE | |
| SCHEMBL3269289 | 0.86 | GBA1 (0.50) | GBA1TSHRSLC2A1BCHEACHE | |
| SCHEMBL7750204 | 0.85 | GBA1 (0.95) | GBA1TSHRTNF | |
| SCHEMBL3652751 | 0.83 | GBA1 (0.91) | GBA1TSHRTNF | |
| SCHEMBL17833025 | 0.83 | GBA1 (1.00) | GBA1TSHRTNF | |
| SCHEMBL14000857 | 0.81 | GBA1 (0.41) | GBA1TSHR | |
| SCHEMBL15326653 | 0.81 | GBA1 (0.41) | GBA1TSHR | |
| SCHEMBL3649428 | 0.81 | GBA1 (0.96) | GBA1TSHRTNF | |
| SCHEMBL15326549 | 0.81 | GBA1 (0.41) | GBA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954320-A4 | INOSITOL POLYPHOSPHATE DERIVATIVES AND METHODS OF USING SAME | UNIV CALIFORNIA (US) | 2001-04-04 | — | — | EP | claimed |
| EP-0954320-A1 | INOSITOL POLYPHOSPHATE DERIVATIVES AND METHODS OF USING SAME | The Regents of the University of California (US) | 1999-11-10 | — | — | EP | claimed |
| US-5880099-A | ALTERING CHLORIDE ION SECRETION ACROSS CELL MEMBRANE BY CONTACTING CELL WITH CELL PERMEABLE AGONIST OR ANTAGONIST OF INOSITOL POLYPHOSPHATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-09 | — | — | US | claimed |
| WO-1998011901-A1 | INOSITOL POLYPHOSPHATE DERIVATIVES AND METHODS OF USING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-03-26 | — | — | WO | claimed |