Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000857 | 1.00 | GBA1 (0.41) | GBA1TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL15326549 | 1.00 | GBA1 (0.41) | GBA1TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL14000856 | 0.91 | GBA1 (0.52) | GBA1TSHRALDH1A1HPGD | |
| SCHEMBL14027874 | 0.89 | GBA1 (0.34) | GBA1TSHRALDH1A1HPGD | |
| SCHEMBL3269289 | 0.89 | GBA1 (0.50) | GBA1TSHRALDH1A1HPGD | |
| SCHEMBL14028643 | 0.82 | PPARG (0.33) | GBA1TSHRHPGD | |
| SCHEMBL8499786 | 0.82 | L3MBTL1 (0.47) | TSHRALDH1A1 | |
| SCHEMBL7749078 | 0.81 | GBA1 (0.70) | GBA1TSHR | |
| SCHEMBL7749062 | 0.81 | GBA1 (0.70) | GBA1TSHR | |
| SCHEMBL16351057 | 0.80 | GBA1 (0.41) | GBA1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013150117-A1 | RADIOTRACER, IN PARTICULAR FOR ALZHEIMER'S DISEASE | UNIVERSITE DE LORRAINE (FR) | 2013-10-10 | — | — | WO | disclosed |