Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 7/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743848 | 1.00 | TSHR (0.75) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL8464950 | 1.00 | TSHR (0.75) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL11337171 | 0.92 | TSHR (0.61) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL9050797 | 0.92 | TSHR (0.61) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL8624811 | 0.92 | TSHR (0.61) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL9015601 | 0.92 | TSHR (0.61) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL9015611 | 0.92 | TSHR (0.61) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL8467609 | 0.88 | TSHR (0.56) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL19468445 | 0.87 | TSHR (1.00) | TSHRALDH1A1TP53CES2HSD17B10 | |
| SCHEMBL19468500 | 0.87 | TSHR (1.00) | TSHRALDH1A1TP53CES2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184180-B1 | COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE | MITSUBISHI PAPER MILLS LIMITED (JP) | 2001-02-06 | — | — | US | disclosed |
| US-5817599-A | COLORLESS DYE PRECURSOR AND REVERSIBLE COLOR DEVELOPER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1998-10-06 | — | — | US | disclosed |