SCHEMBL7749108

SCHEMBL7749108

CCCCCCCCCCCCCCCCC(C)SCCNC(=O)NC(=O)COc1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 3/20 0.42
NR5A1 Q13285 1/20 0.41
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
TSHR P16473 1/20 0.40
RECQL P46063 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LTA4H P09960 1/20 0.37
EGFR P00533 6/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7747879 0.93 TSHR (0.47) ALDH1A1NR5A1LMNASMN1; SMN2TSHR
SCHEMBL7749156 0.91 TSHR (0.40) KDM4ENR5A1LMNASMN1; SMN2TSHR
SCHEMBL7747954 0.90 NR5A1 (0.45) NR5A1LTA4H
SCHEMBL7743827 0.87 NR5A1 (0.49) NR5A1TSHRKMT2ALTA4H
SCHEMBL7749322 0.87 NR5A1 (0.49) NR5A1TSHRKMT2ALTA4H
SCHEMBL7749313 0.86 NR5A1 (0.51) KDM4ENR5A1TSHRLTA4H
SCHEMBL7750813 0.85 NR5A1 (0.44) NR5A1LTA4H
SCHEMBL7750800 0.84 KDM4E (0.44) KDM4EALDH1A1NR5A1LMNASMN1; SMN2
SCHEMBL7750897 0.84 NR5A1 (0.46) NR5A1TSHRLTA4H
SCHEMBL7749142 0.84 NR5A1 (0.46) NR5A1TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed