SCHEMBL7749289

SCHEMBL7749289

CC(=O)c1c(Cl)nc(Cl)nc1Cl

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.39
POLB P06746 2/20 0.38
PABPC1 P11940 1/20 0.37
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
LMNA P02545 2/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
THRB P10828 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396015 0.82 KMT2A (0.43) SMN1; SMN2ALDH1A1MAPK1POLBPABPC1
SCHEMBL16507376 0.82 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1MAPK1POLBPABPC1
SCHEMBL20067834 0.77 PPARG (0.41) SMN1; SMN2ALDH1A1MAPK1POLBPABPC1
SCHEMBL1989330 0.76 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1MAPK1POLBALOX15
SCHEMBL4082477 0.76 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1MAPK1POLBALOX15
SCHEMBL9135606 0.74 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1MAPK1POLBALOX15
Hydrochloric Acid SCHEMBL10581422 0.74 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1MAPK1POLBALOX15
SCHEMBL9137101 0.74 POLB (0.52) SMN1; SMN2ALDH1A1MAPK1POLBALOX15
Acetone SCHEMBL10636901 0.74 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1MAPK1POLBALOX15
SCHEMBL4083135 0.73 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1MAPK1POLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1068390-A1 METHOD FOR IMPROVED WET STRENGTH PAPER Kimberly-Clark Worldwide, Inc. (US) 2001-01-17 EP disclosed
WO-1999045201-A1 METHOD FOR IMPROVED WET STRENGTH PAPER KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-09-10 WO disclosed
US-5935383-A Method for improved wet strength paper KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-08-10 US disclosed
US-4855410-A Process for the preparation of fibre-reactive azo compounds containing a phenylenediamine diazo component CIBA-GEIGY CORPORATION (US) 1989-08-08 US disclosed
EP-0213071-B1 PROCESS FOR THE PREPARATION OF FIBRE-REACTIVE AZO COMPOUNDS CIBA-GEIGY AG (CH) 1989-03-08 EP disclosed
EP-0132223-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-09-30 EP disclosed
EP-0213071-A1 Process for the preparation of fibre-reactive azo compounds CIBA-GEIGY AG (CH) 1987-03-04 EP disclosed
US-4631065-A Reactive dyes, process for their preparation and use thereof CIBA-GEIGY CORPORATION (US) 1986-12-23 US disclosed
US-4568350-A Cold pad-batch process for dyeing silk or silk-containing fiber blends with reactive dyes CIBA-GEIGY CORPORATION (US) 1986-02-04 US disclosed
US-4560388-A WITH SULFO GROUP CONTAINING FIBER REACTIVE DYE CIBA-GEIGY CORPORATION (US) 1985-12-24 US disclosed
US-4330469-A Reactive dyes, processes for their manufacture and their use CIBA-GEIGY CORPORATION (US) 1982-05-18 US disclosed
US-4283331-A FIBER-REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4210582-A FIBER-REACTIVE YELLOW DYES FOR WOOL CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4001203-A Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed