Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315990 | 0.90 | AGTR1 (0.43) | AGTR1ABCG2SMN1; SMN2POLBRAB9A | |
| SCHEMBL3875056 | 0.89 | AGTR1 (0.49) | AGTR1ABCG2SMN1; SMN2POLBRAB9A | |
| SCHEMBL21083692 | 0.88 | AGTR1 (0.42) | AGTR1ABCG2SMN1; SMN2POLBRAB9A | |
| SCHEMBL8783660 | 0.88 | SMN1; SMN2 (0.40) | AGTR1ABCG2SMN1; SMN2POLBRAB9A | |
| SCHEMBL6624598 | 0.85 | SMN1; SMN2 (0.42) | AGTR1SMN1; SMN2POLBRAB9AL3MBTL1 | |
| SCHEMBL5091164 | 0.83 | POLB (0.43) | AGTR1SMN1; SMN2POLBRAB9AL3MBTL1 | |
| SCHEMBL30743612 | 0.82 | ABCG2 (0.55) | AGTR1ABCG2SMN1; SMN2POLBRAB9A | |
| SCHEMBL9177078 | 0.81 | AGTR1 (0.39) | AGTR1ABCG2POLBHPGDALDH1A1 | |
| SCHEMBL2161550 | 0.81 | ABCG2 (0.41) | AGTR1ABCG2SMN1; SMN2POLBRAB9A | |
| SCHEMBL21083769 | 0.80 | AGTR1 (0.41) | AGTR1ABCG2SMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491971-A | Chiral ((4-methyl-2-propyl-1H-benzimidazole-6-amide)-1-radical) methyl diphenyl compound, as well as preparation method and application thereof | BEIJING INST TECHNOLOGY | 2012-06-13 | — | — | CN | disclosed |
| US-6214999-B1 | A BROMINATING AGENT IS REACTED IN A 2 PHASE MEDIUM, UNDER EFFECT PHOTO-IRRADIATION WITH BIPHENYL DERIVATIVE | SANOFI-SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |