Methoprene

Methoprene

SCHEMBL7749411

COC(C)(C)CCCC(C)C/C=C/C(C)=C/C(=O)OC(C)C.COC(C)(C)CCCC(C)C/C=C/C(C)=C/C(=O)OC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 1.00
▸ LMNA P02545 1/20 1.00
▸ CYP3A4 P08684 1/20 1.00
▸ TDP1 Q9NUW8 1/20 1.00
▸ HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoprene SCHEMBL28643024 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4TDP1HCAR2
Methoprene SCHEMBL43694 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4TDP1HCAR2
Methoprene SCHEMBL1190845 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4TDP1HCAR2
Methoprene SCHEMBL27840843 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4TDP1HCAR2
Methoprene SCHEMBL851922 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4TDP1HCAR2
Methoprene SCHEMBL19795 1.00 ALDH1A1 (1.00) ALDH1A1LMNACYP3A4TDP1HCAR2
Methoprene SCHEMBL11460879 0.99 ALDH1A1 (0.98) ALDH1A1LMNACYP3A4TDP1
SCHEMBL11865825 0.98 ALDH1A1 (0.95) ALDH1A1LMNACYP3A4TDP1
Methoprene SCHEMBL11470834 0.98 ALDH1A1 (0.95) ALDH1A1LMNACYP3A4TDP1HCAR2
SCHEMBL11865831 0.98 ALDH1A1 (0.95) ALDH1A1LMNACYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970544-B2 Antibodies GENMAB A/S (DK) 2024-04-30 — — US disclosed
EP-4334359-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING BISPECIFIC ANTIBODIES BINDING TO B7H4 AND CD3 Genmab A/S (DK) 2024-03-13 — — EP disclosed
CN-117396509-A Pharmaceutical composition comprising a bispecific antibody binding to B7H4 and CD3 健玛保 2024-01-12 — — CN disclosed
CN-111670198-B Binding proteins for the human thrombin receptor PAR4 莫纳什大学 2023-12-15 — — CN disclosed
US-20230257479-A1 BISPECIFIC ANTIBODIES BINDING TO 5T4 AND CD3 FOR USE IN TREATMENT OF CANCER WILMINGTON TRUST, NATIONAL ASSOCIATION 2023-08-17 — — US disclosed
EP-4121456-A1 ANTIBODIES BINDING TO B7H4 Genmab A/S (DK) 2023-01-25 — — EP disclosed
CN-115298221-A Antibodies that bind B7H4 健玛保 2022-11-04 — — CN disclosed
EP-4028424-A1 BISPECIFIC ANTIBODIES BINDING TO 5T4 AND CD3 FOR USE IN TREATMENT OF CANCER Genmab A/S (DK) 2022-07-20 — — EP disclosed
US-11261254-B1 Antibodies GENMAB A/S (DK) 2022-03-01 — — US disclosed
US-20220048999-A1 ANTIBODIES WILMINGTON TRUST, NATIONAL ASSOCIATION 2022-02-17 — — US disclosed
EP-3233919-A1 DICAM-SPECIFIC ANTIBODIES AND USES THEREOF Centre Hospitalier De L'Universite de Montreal (CA) 2017-10-25 — — EP disclosed
WO-2016095046-A1 DICAM-SPECIFIC ANTIBODIES AND USES THEREOF VAL-CHUM, LIMITED PARTNERSHIP (CA) 2016-06-23 — — WO disclosed
US-9221918-B2 Antigen binding polypeptides ARGEN-X B.V. (NL) 2015-12-29 — — US disclosed
US-20150239990-A1 ANTIGEN BINDING POLYPEPTIDES argenx BV (BE) 2015-08-27 — — US disclosed
WO-2013012733-A1 HETERODIMERIC FC REGIONS, BINDING MOLECULES COMPRISING SAME, AND METHODS RELATING THERETO BIOGEN IDEC MA INC. (US) 2013-01-24 — — WO disclosed
WO-2001075856-A1 DNA ANALYSIS SOFTWARE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-10-11 — — WO disclosed
US-6001382-A COMPRISING COMPLEXES FOR TREATING A POPULATION OF ONE OR MORE AQUATIC ORGANISMS IN A COLUMN OF WATER, THE COMPLEXES COMPRISE AT LEAST ONE SYSTEM WHEREIN THE SYSTEM COMPRISES AT LEAST ONE BIOACTIVE AGENT, A CARRIER, AN ORGANIC PLASTICIZER LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-12-14 — — US disclosed
US-5858386-A CONTROLLED RELEASE OF BIOACTIVE AGENTS ON DRY PRE-FLOODED LAND; WATER SOLUBLE, BIODEGRADABLE COATING OF FATTY ALCOHOLS, FATTY ACIDS, FATTY ESTERS OR PHTHALYL ESTERS; MOSQUITO, WEED CONTROL; NO SUPERABSORBENT POLYMERS LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-01-12 — — US disclosed
US-5858384-A Controlled delivery compositions and processes for treating organisms in a column of water or on land LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-01-12 — — US disclosed
US-5698210-A SUSTAINED RELEASE OF INSECTICIDES, PARASITICIDES, HERBICIDES LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1997-12-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150239990-A1 ANTIGEN BINDING POLYPEPTIDES IGLV6-57, IGSF11, CD74 ALDH1A1 4137/4885LMNA 4769/4885CYP3A4 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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