Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924940 | 0.88 | PDE4A (0.43) | CA12CA1CA9CA2CYP2D6 | |
| SCHEMBL3169457 | 0.85 | CA12 (0.40) | CA12CA1CA9CA2LMNA | |
| SCHEMBL2422782 | 0.80 | CA12 (0.41) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL8770831 | 0.80 | PDE4A (0.36) | CA12CA1CA9CA2CYP2D6 | |
| SCHEMBL15216630 | 0.79 | CA12 (0.40) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL20472611 | 0.77 | CA12 (0.45) | CA12CA1CA9CA2MEN1 | |
| SCHEMBL8622413 | 0.77 | CA12 (0.45) | CA12CA1CA9CA2MEN1 | |
| SCHEMBL8618803 | 0.77 | CA12 (0.45) | CA12CA1CA9CA2MEN1 | |
| SCHEMBL8816793 | 0.77 | GPR84 (0.45) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL3164812 | 0.77 | PDE4A (0.37) | CA12CA1CA9CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042200-A1 | CATIONIC AMPHIPHILES FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 2001-06-14 | — | — | WO | disclosed |