Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.47 |
| ▸ | MMP2 | P08253 | 7/20 | 0.47 |
| ▸ | MMP1 | P03956 | 7/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7749551 | 0.99 | MMP13 (0.46) | MMP13MMP2MMP1ADAMTS4MMP9 | |
| SCHEMBL7748779 | 0.89 | MMP13 (0.49) | MMP13MMP2MMP1ADAMTS4FFAR1 | |
| SCHEMBL7686385 | 0.89 | MMP13 (0.50) | MMP13MMP2MMP1ADAMTS4MMP9 | |
| SCHEMBL7686382 | 0.89 | MMP13 (0.50) | MMP13MMP2MMP1ADAMTS4MMP9 | |
| Hydrochloric Acid SCHEMBL7748736 | 0.89 | MMP13 (0.48) | MMP13MMP2MMP1ADAMTS4FFAR1 | |
| Hydrochloric Acid SCHEMBL7681488 | 0.88 | MMP13 (0.49) | MMP13MMP2MMP1ADAMTS4MMP9 | |
| Hydrochloric Acid SCHEMBL7681477 | 0.88 | MMP13 (0.49) | MMP13MMP2MMP1ADAMTS4MMP9 | |
| Hydrochloric Acid SCHEMBL7748775 | 0.83 | MMP13 (0.48) | MMP13MMP2MMP1ADAMTS4ALDH1A1 | |
| SCHEMBL7683556 | 0.78 | MMP13 (0.53) | MMP13MMP2MMP1MMP9 | |
| SCHEMBL7683552 | 0.78 | MMP13 (0.53) | MMP13MMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983258-A4 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO CO (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0983258-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039316-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |