SCHEMBL775002

SCHEMBL775002

CC(C)(C)OC(=O)Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.56
NAPRT Q6XQN6 1/20 0.52
HSD17B10 Q99714 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.51
GAA P10253 2/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51
CYP17A1 P05093 2/20 0.51
TP53 P04637 1/20 0.50
EPHX1 P07099 1/20 0.50
TSHR P16473 1/20 0.50
EPHX2 P34913 1/20 0.50
CDK9 P50750 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
PSMB8 P28062 1/20 0.49
PDK1 Q15118 2/20 0.49
PDK2 Q15119 2/20 0.49
PDK3 Q15120 2/20 0.49
PDK4 Q16654 2/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27942342 0.93 PDK1 (0.51) NAMPTNAPRTHSD17B10SMN1; SMN2GAA
SCHEMBL9479696 0.93 MAPT (0.58) NAMPTHSD17B10SMN1; SMN2GAAALDH1A1
Alcohol SCHEMBL4315662 0.93 NAMPT (0.51) NAMPTNAPRTHSD17B10SMN1; SMN2GAA
SCHEMBL3461792 0.93 SMN1; SMN2 (0.59) NAMPTSMN1; SMN2CYP17A1TP53EPHX1
SCHEMBL31300042 0.90 GAA (0.60) NAMPTHSD17B10SMN1; SMN2GAAALDH1A1
SCHEMBL13055402 0.90 CYP17A1 (0.59) NAMPTSMN1; SMN2GAAALDH1A1CYP17A1
SCHEMBL18570243 0.89 CYP17A1 (0.61) NAMPTSMN1; SMN2ALDH1A1HTTCYP17A1
SCHEMBL17526122 0.88 NAMPT (0.73) NAMPTSMN1; SMN2ALDH1A1HTTMEN1
SCHEMBL3460916 0.88 KMT2A (0.55) HSD17B10SMN1; SMN2HTTCYP17A1TP53
SCHEMBL17346615 0.88 NAPRT (0.52) NAPRTHSD17B10SMN1; SMN2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1091 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977844-A Preparation method of N-BOC-aniline derivative 上海泰坦科技股份有限公司 2025-05-13 CN claimed
CN-118930788-B Preparation method and application of amino-terminated quaternary ammonium salt polymer material 临沂斯科瑞聚氨酯材料有限公司 2025-05-06 CN claimed
CN-118930788-A Preparation method and application of amino-terminated quaternary ammonium salt polymer material 临沂斯科瑞聚氨酯材料有限公司 2024-11-12 CN claimed
CN-114989236-B Single molecular weight amphiphilic oligomer with azobenzene-containing main chain and sugar-containing side chain, and preparation method and application thereof 苏州大学 2024-03-15 CN claimed
CN-117466815-A Synthesis method of azaanthrone compound 西北工业大学 2024-01-30 CN claimed
WO-2023231091-A1 SINGLE-MOLECULAR-WEIGHT AMPHIPHILIC OLIGOMER HAVING MAIN CHAIN CONTAINING AZOBENZENE AND SIDE CHAIN CONTAINING SUGAR, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州大学 2023-12-07 WO claimed
CN-113214113-B Preparation method of aniline para-trifluoromethylated derivative 苏州大学 2022-10-14 CN claimed
CN-114989236-A Single molecular weight amphiphilic oligomer with main chain containing azobenzene and side chain containing sugar as well as preparation method and application thereof 苏州大学 2022-09-02 CN claimed
CN-114805137-A Compound, oat bran extract and application of oat bran extract in preparation of product with antioxidant or anti-inflammatory effects 深圳海创生物科技有限公司 2022-07-29 CN claimed
CN-104093709-A Imidazolylketone derivatives as aldosterone synthase inhibitors HOFFMANN LA ROCHE 2014-10-08 CN claimed
CN-101048383-A Gonadotropin releasing hormone receptor antagonists WYETH CORP (US) 2007-10-03 CN claimed
US-20070149484-A1 NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES ZENTARIS GMBH (DE) 2007-06-28 US claimed
CN-1960726-A Composition comprising a jnk inhibitor and cyclosporin APPLIED RESEARCH SYSTEMS (AN) 2007-05-09 CN claimed
CN-1863752-A Copper catalyzed arylation RHODIA PHARMA SOLUTIONS INC (US) 2006-11-15 CN claimed
CN-1252067-C Benzazole derivatives and their use as JNK modulators APPLIED RESEARCH SYSTEMS (AN) 2006-04-19 CN claimed
CN-1694873-A Vanilloid receptor ligands and their use in treatments AMGEN INC (US) 2005-11-09 CN claimed
CN-1211359-C Novel phenylalkoxy-phenyl derivatives ASTRAZENECA AB (SE) 2005-07-20 CN claimed
CN-1433414-A Benzazole derivatives and their use as JNK modulators APPLIED RESEARCH SYSTEMS (NL) 2003-07-30 CN claimed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN claimed
US-5079383-A With A Methylating Agent Using A Zinc Halide Catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-01-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149484-A1 NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES MAP4K2, MAP3K15, MAP3K5 NAMPT 980/4885NAPRT 888/4885HSD17B10 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.