Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627 | 0.88 | EP300 (1.00) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29412863 | 0.88 | EP300 (1.00) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5705313 | 0.82 | EP300 (0.89) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4666463 | 0.80 | EP300 (0.63) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29527262 | 0.80 | CCR4 (0.64) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29473710 | 0.80 | EP300 (0.63) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL179796 | 0.80 | CCR4 (0.64) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL38666492 | 0.79 | EP300 (0.67) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14198859 | 0.76 | EP300 (0.79) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28014361 | 0.76 | EP300 (0.79) | EP300KDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326142-B1 | MEASURING BINDING OF POLYNUCLEOTIDE TO PROTEIN; LABEL NUCLEOTIDE SEQUENCES, MEASURE POLARIZATION OF FLUORESCENT EMISSION, INCUBATE NUCLEOTIDE SEQUENCE WITH PROTEIN, MEASURE POLARIZATION AND COMPARE, DETECT COMPLEX FORMATION | PANVERA CORPORATED | 2001-12-04 | — | — | US | disclosed |
| EP-0672191-B1 | QUANTITATIVE DETECTION OF MACROMOLECULES WITH FLUORESCENT OLIGONUCLEOTIDES | RP TECHNOLOGIES INC (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-0672191-A4 | QUANTITATIVE DETECTION OF MACROMOLECULES WITH FLUORESCENT OLIGONUCLEOTIDES. | RP TECHNOLOGIES INC (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5756292-A | Quantitative detection of macromolecules with fluorescent oligonucleotides | R-P TECHNOLOGIES, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0672191-A1 | QUANTITATIVE DETECTION OF MACROMOLECULES WITH FLUORESCENT OLIGONUCLEOTIDES | R-P TECHNOLOGIES, INC (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5445935-A | Measuring changes in polarization | Life Technologies Corporation | 1995-08-29 | — | — | US | disclosed |
| WO-1994012665-A1 | QUANTITATIVE DETECTION OF MACROMOLECULES WITH FLUORESCENT OLIGONUCLEOTIDES | R-P TECHNOLOGIES, INC. (US) | 1994-06-09 | — | — | WO | disclosed |