SCHEMBL6627

SCHEMBL6627

CCN(CC)c1ccc2c(C)c(-c3ccc(N4C(=O)C=CC4=O)cc3)c(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 1.00
ALDH1A1 P00352 10/20 0.71
KDM4E B2RXH2 8/20 0.71
MAPT P10636 6/20 0.71
HPGD P15428 5/20 0.71
L3MBTL1 Q9Y468 5/20 0.71
HIF1A Q16665 2/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
HTT P42858 5/20 0.56
TDP1 Q9NUW8 4/20 0.56
ATM Q13315 6/20 0.54
GLA P06280 6/20 0.54
GAA P10253 2/20 0.54
KLK7 P49862 1/20 0.54
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
CASP1 P29466 5/20 0.49
CASP7 P55210 5/20 0.49
HSD17B10 Q99714 5/20 0.49
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412863 1.00 EP300 (1.00) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL5705313 0.94 EP300 (0.89) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL14198859 0.89 EP300 (0.79) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL28014361 0.88 EP300 (0.79) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL7750137 0.88 EP300 (0.78) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL13869309 0.87 ALDH1A1 (0.86) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL28974039 0.83 EP300 (0.71) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL28720726 0.83 ALDH1A1 (0.75) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL8132354 0.83 ALDH1A1 (1.00) EP300ALDH1A1KDM4EMAPTHPGD
SCHEMBL5590828 0.83 ALDH1A1 (0.78) EP300ALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584915-B2 Glyphosate biosensor THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-03-24 US claimed
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-23 US claimed
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377898-B1 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377904-B1 UREA BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-4100956-A1 IMPROVED PROCESSES FOR RATIONALLY-DESIGNING AND PRODUCING BIOMOLECULES Her Majesty The Queen in Right of Canada, as Represented by The Minister of Agriculture and Agri-Food (CA) 2022-12-14 EP claimed
US-20220276241-A1 GLYPHOSATE BIOSENSOR THE TRUSTEES OF INDIANA UNIVERSITY 2022-09-01 US claimed
US-20220244266-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2022-08-04 US claimed
EP-4007767-A1 GLYPHOSATE BIOSENSOR The Trustees of Indiana University (US) 2022-06-08 EP claimed
US-20210371899-A1 METHOD AND KIT FOR PESTICIDES DETECTION, AND PLASMID, BACULOVIRUS, CELL AND METHOD OF PREPARING THE SAME FOR PESTICIDE DETECTIONS ACADEMIA SINICA (TW) 2021-12-02 US claimed
US-20180328935-A1 GLUCOSE BISENSORS AND USES THEREOF DUKE UNIVERSITY 2018-11-15 US claimed
EP-3377904-A2 UREA BIOSENSORS AND USES THEREOF Duke University (US) 2018-09-26 EP claimed
EP-3377898-A2 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF Duke University (US) 2018-09-26 EP claimed
EP-3377643-A1 GLUCOSE BIOSENSORS AND USES THEREOF Duke University (US) 2018-09-26 EP claimed
EP-1175509-B1 IMMOBILIZED ENZYMES AS BIOSENSORS FOR CHEMICAL TOXINS US ARMY MED RES MAT COMMAND (US) 2006-09-20 EP claimed
US-6406876-B1 DECTECTORS FOR ANALYZING SAMPLE OF ORGANOPHOSPHOROUS OR ORGANOSULFUR COMPOUND THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2002-06-18 US claimed
EP-1175509-A2 IMMOBILIZED ENZYMES AS BIOSENSORS FOR CHEMICAL TOXINS U.S. Army Medical Research and Materiel Command (US) 2002-01-30 EP claimed
WO-2000065081-A2 IMMOBILIZED ENZYMES AS BIOSENSORS FOR CHEMICAL TOXINS U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2000-11-02 WO claimed
EP-0715721-A1 PHOSPHATE ASSAY MEDICAL RESEARCH COUNCIL (GB) 1996-06-12 EP claimed
WO-1995002825-A1 PHOSPHATE ASSAY MEDICAL RESEARCH COUNCIL (GB) 1995-01-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180328935-A1 GLUCOSE BISENSORS AND USES THEREOF SLC2A4, GCKR, SLC2A1 EP300 3833/4885ALDH1A1 1390/4885KDM4E 3602/4885
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 EP300 3589/4885ALDH1A1 1398/4885KDM4E 3773/4885
US-20220244266-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 EP300 3589/4885ALDH1A1 1398/4885KDM4E 3773/4885
US-12584915-B2 Glyphosate biosensor TMIGD3, BTD, PTMS EP300 3830/4885ALDH1A1 4001/4885KDM4E 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.