Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.51 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.51 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997112 | 0.86 | IAPP (0.51) | BIDMCL1BCL2L1BAK1 | |
| Pimelic Acid SCHEMBL8652092 | 0.86 | HDAC11 (0.50) | PPARGPPARAMAPTRXFP1 | |
| SCHEMBL8389559 | 0.85 | F13A1 (0.51) | PPARGPPARAF13A1MAPTRXFP1 | |
| SCHEMBL27673297 | 0.85 | F13A1 (0.51) | PPARGPPARAF13A1MAPTRXFP1 | |
| SCHEMBL31169746 | 0.85 | F13A1 (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL31086218 | 0.85 | F13A1 (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL20854050 | 0.83 | CYSLTR2 (0.49) | PPARGPPARAF13A1MAPTRXFP1 | |
| SCHEMBL7399102 | 0.83 | IAPP (0.57) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL31169744 | 0.83 | F13A1 (0.49) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28122719 | 0.83 | F13A1 (0.49) | F13A1MAPTRXFP1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836382-A4 | NEW CRYPTOPHYCINS | UNIV HAWAII (US) | 2001-01-17 | — | — | EP | disclosed |
| US-5952298-A | NOVEL CRYPTOPHYCIN COMPOUNDS PRODUCED BY CYANOBACTERIA OF GENUS NOSTOC USED AS ANTIPROLIFERATIVE AGENTS IN COMBINATION WITH ANTIMITOTIC AGENTS TO TREAT CELLS WITH DRUG RESISTANT PHENOTYPES, AND TO TREAT NEOPLASIA | THE UNIVERSITY OF HAWAII (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0836382-A1 | NEW CRYPTOPHYCINS | UNIVERSITY OF HAWAII (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1996039829-A9 | NEW CRYPTOPHYCINS | — | 1997-02-20 | — | — | WO | disclosed |
| WO-1996039829-A1 | NEW CRYPTOPHYCINS | UNIVERSITY OF HAWAII (US) | 1996-12-19 | — | — | WO | disclosed |