Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750342 | 1.00 | SRD5A1 (0.54) | SRD5A1SRD5A2 | |
| SCHEMBL7750269 | 0.91 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL7749938 | 0.91 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL7750265 | 0.91 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL7749933 | 0.91 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL7749959 | 0.90 | SRD5A1 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL7749956 | 0.90 | SRD5A1 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL7745500 | 0.88 | SRD5A1 (0.59) | SRD5A1SRD5A2 | |
| SCHEMBL7750361 | 0.88 | HSD17B7 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL7751296 | 0.88 | HSD17B7 (0.61) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649306-B1 | ESTER DERIVATIVES OF 4-AZA-STEROIDS | MERCK & CO INC (US) | 2001-01-10 | — | — | EP | claimed |
| EP-0649306-B1 | ESTER DERIVATIVES OF 4-AZA-STEROIDS | MERCK & CO INC (US) | 2001-01-10 | — | — | EP | disclosed |
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5610162-A | ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1997-03-11 | — | — | US | disclosed |