Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750487 | 1.00 | LMNA (0.42) | LMNARARBTP53MAPTLTA4H | |
| SCHEMBL7750426 | 1.00 | LMNA (0.42) | LMNARARBTP53MAPTLTA4H | |
| SCHEMBL7750435 | 1.00 | LMNA (0.42) | LMNARARBTP53MAPTLTA4H | |
| SCHEMBL9120827 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 | |
| SCHEMBL9121319 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 | |
| SCHEMBL9119795 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 | |
| SCHEMBL9120384 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 | |
| SCHEMBL9119797 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 | |
| SCHEMBL9120381 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 | |
| SCHEMBL9121323 | 0.94 | RARB (0.46) | LMNARARBTP53LTA4HNR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| US-5759443-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-02 | — | — | US | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |