Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8119145 | 0.99 | TPSAB1 (0.37) | TPSAB1TDP1MEN1KMT2ALMNA | |
| SCHEMBL4653109 | 0.92 | TPSAB1 (0.39) | TPSAB1TDP1MEN1KMT2AITGB3 | |
| SCHEMBL8121426 | 0.92 | TPSAB1 (0.39) | TPSAB1TDP1MEN1KMT2AITGB3 | |
| SCHEMBL30905434 | 0.91 | CNR1 (0.41) | TPSAB1TDP1MEN1KMT2ACNR1 | |
| SCHEMBL1389118 | 0.91 | CNR1 (0.41) | TPSAB1TDP1MEN1KMT2ACNR1 | |
| SCHEMBL8121296 | 0.91 | F2 (0.38) | TPSAB1TDP1MEN1KMT2AITGB3 | |
| SCHEMBL7750689 | 0.90 | MEN1 (0.42) | TDP1MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL4651831 | 0.90 | CNR1 (0.42) | TPSAB1TDP1MEN1KMT2ACNR1 | |
| SCHEMBL8528076 | 0.90 | TPSAB1 (0.39) | TPSAB1TDP1MEN1KMT2ANPY1R | |
| SCHEMBL1593414 | 0.89 | NPY1R (0.42) | TDP1CNR1NPY1RCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |