Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.67 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.67 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.52 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750694 | 1.00 | PRKCA (0.67) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL9472418 | 0.92 | PRKCA (0.71) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL9861357 | 0.92 | PRKCA (0.71) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL9472428 | 0.92 | PRKCA (0.71) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL9861368 | 0.92 | PRKCA (0.71) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL8021306 | 0.86 | PRKCA (0.63) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL8021308 | 0.86 | PRKCA (0.63) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL14758255 | 0.86 | PRKCA (0.76) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL25439708 | 0.84 | PRKCA (0.78) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL20499894 | 0.84 | PRKCA (0.78) | PRKCAPRKCEPRKCQPRKCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835238-B1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-21 | — | — | EP | disclosed |
| US-6060455-A | AGGREGATION WITH RNA OR DNA; DELIVERY INTO CELLS | BOEHRINGER MANNHEIM GMBH (DE) | 2000-05-09 | — | — | US | disclosed |
| EP-0835238-A1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | Roche Diagnostics GmbH (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997000241-A1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-03 | — | — | WO | disclosed |