Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961034 | 0.79 | HDAC6 (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7745011 | 0.79 | HSP90AB1 (0.47) | HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL7750736 | 0.75 | ADORA2A (0.52) | ALDH1A1 | |
| SCHEMBL7749604 | 0.73 | HPRT1 (0.50) | ALDH1A1HSD17B10 | |
| SCHEMBL23710675 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14642669 | 0.70 | CDK1 (0.56) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4064570 | 0.70 | MERTK (0.39) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4064578 | 0.70 | MERTK (0.39) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL1883249 | 0.70 | KDM4E (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6950568 | 0.70 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019404-A4 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMW SCIENT IND RES ORG (AU) | 2001-07-04 | — | — | EP | disclosed |
| EP-1019404-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999012927-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-18 | — | — | WO | disclosed |