Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752260 | 0.99 | MAPK8 (0.45) | MAPK8MAPK10RAB9AKDM4ENPC1 | |
| SCHEMBL7752202 | 0.80 | CA1 (0.52) | KDM4ECA1CA2LNPEPHDAC8 | |
| SCHEMBL7871463 | 0.77 | HDAC1 (0.56) | KDM4ECA1CA2LNPEPHDAC1 | |
| SCHEMBL16042130 | 0.77 | CA1 (0.50) | KDM4ECA1CA2LNPEPHDAC1 | |
| SCHEMBL23286785 | 0.76 | CA1 (0.61) | KDM4ECA1CA2LNPEPHDAC8 | |
| SCHEMBL7752228 | 0.75 | PPM1D (0.43) | CA1CA2LNPEPHDAC8HDAC1 | |
| SCHEMBL13175564 | 0.74 | KMT2A (0.49) | RAB9AKDM4ENPC1SMN1; SMN2NPSR1 | |
| SCHEMBL13017388 | 0.74 | CA1 (0.53) | KDM4ESMN1; SMN2CA1CA2LNPEP | |
| SCHEMBL5363438 | 0.73 | CA1 (0.51) | RAB9AKDM4ENPC1SMN1; SMN2CA1 | |
| SCHEMBL13575472 | 0.73 | HTT (0.50) | RAB9AKDM4ENPC1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069113-A1 | BENZIMIDAZOLE DERIVATIVE | Kureha Chemical Industry Co., Ltd. (JP) | 2001-01-17 | — | — | EP | disclosed |