Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PPM1D | O15297 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286785 | 0.88 | CA1 (0.61) | CA1CA2LOXL2LNPEPALDH1A1 | |
| SCHEMBL16042130 | 0.85 | CA1 (0.50) | CA1CA2LOXL2LNPEPALDH1A1 | |
| SCHEMBL7871463 | 0.85 | HDAC1 (0.56) | CA1CA2LNPEPKMT2AALDH1A1 | |
| SCHEMBL13017388 | 0.82 | CA1 (0.53) | CA1CA2LOXL2LNPEPMEN1 | |
| SCHEMBL7567524 | 0.82 | CA1 (0.50) | CA1CA2LOXL2PPM1DL3MBTL1 | |
| SCHEMBL5363438 | 0.81 | CA1 (0.51) | CA1CA2LOXL2LNPEPKMT2A | |
| SCHEMBL7751013 | 0.80 | MAPK8 (0.44) | CA1CA2LOXL2LNPEPALDH1A1 | |
| SCHEMBL7752260 | 0.79 | MAPK8 (0.45) | CA1CA2LNPEPMEN1KMT2A | |
| SCHEMBL23286843 | 0.79 | LNPEP (0.46) | CA1CA2LOXL2LNPEPALDH1A1 | |
| SCHEMBL2885615 | 0.78 | CA1 (0.51) | CA1CA2LOXL2LNPEPPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242445-B1 | CURATIVE EFFECTS FOR CARDIAC AND NEPHRIC DISEASES, ALTHOUGH HAVING LITTLE ACTION ON BLOOD-PRESSURE. | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1069113-A1 | BENZIMIDAZOLE DERIVATIVE | Kureha Chemical Industry Co., Ltd. (JP) | 2001-01-17 | — | — | EP | disclosed |