Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 7/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749787 | 0.81 | METAP2 (0.39) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL7982121 | 0.80 | METAP2 (0.49) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL6444605 | 0.71 | METAP2 (0.47) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL14921560 | 0.71 | METAP2 (0.47) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL14921519 | 0.69 | METAP2 (0.45) | METAP2METAP1PLAUNCF1PIM1 | |
| Hydrochloric Acid SCHEMBL5833545 | 0.68 | METAP2 (0.44) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL10982506 | 0.65 | METAP2 (0.47) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL15668088 | 0.63 | GAA (0.48) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL17931882 | 0.62 | PLAU (0.47) | METAP2METAP1PLAUNCF1PIM1 | |
| SCHEMBL17931886 | 0.62 | METAP2 (0.42) | METAP2METAP1PLAUNCF1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297401-B1 | A 3-NITROSALICYLAMIDE DERIVATIVE EFFECTIVE AGAINST PLANT PYTOPATHOGENS | DOW AGROSCIENCES LLC | 2001-10-02 | — | — | US | disclosed |
| EP-1035772-A4 | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | DOW AGROSCIENCES LLC (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1035772-A1 | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | Dow AgroSciences LLC (US) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999027783-A1 | FUNGICIDAL COMPOSITIONS AND METHODS, AND COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | DOW AGROSCIENCES LLC (US) | 1999-06-10 | — | — | WO | disclosed |