Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3918259 | 0.84 | PTGER1 (0.47) | ALDH1A1PTGER1CYP2C9MRGPRX4CYP19A1 | |
| SCHEMBL16355726 | 0.81 | ALDH1A1 (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12980387 | 0.78 | PTGER1 (0.54) | NPC1RAB9APTGER1CYP2C9KMT2A | |
| SCHEMBL7378150 | 0.77 | ALDH1A1 (0.53) | NPC1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL7743982 | 0.77 | ALDH1A1 (0.64) | NPC1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL30791439 | 0.77 | MAOB (0.44) | — | |
| SCHEMBL12154898 | 0.76 | MRGPRX4 (0.38) | NPC1HPGDRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3915942 | 0.75 | PTGER1 (0.58) | NPC1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7375458 | 0.75 | CYP19A1 (0.51) | NPC1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL31376019 | 0.75 | SLC6A4 (0.47) | NPC1ALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |