Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754618 | 0.95 | ESR1 (0.55) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL7751068 | 0.93 | TYR (0.50) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL7755513 | 0.91 | ESR1 (0.50) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL7754603 | 0.88 | TYR (0.54) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL7754180 | 0.88 | KDM4E (0.50) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL7757054 | 0.84 | CYP3A4 (0.50) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL6022639 | 0.84 | TYR (0.64) | TYRCYP3A4MEN1TP53ALOX5 | |
| SCHEMBL10591054 | 0.81 | CYP3A4 (0.56) | CYP3A4MEN1TP53MAPTKMT2A | |
| SCHEMBL4370686 | 0.80 | TYR (0.81) | TYRESR1CYP19A1ESR2CYP3A4 | |
| SCHEMBL7755725 | 0.80 | CYP3A4 (0.47) | TYRCYP3A4MEN1TP53ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811595-B1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI CHEMICALS INC (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-5880314-A | DEPIGMENTING; SAFE TO SKIN, STORAGE STABLE | MITSUI CHEMICALS, INC. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811595-A1 | HYDROCHALCONE DERIVATIVES, COMESTIC COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PREPARATION OF BOTH | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-12-10 | — | — | EP | disclosed |