Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181927 | 0.81 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL5162313 | 0.76 | CHRNB2 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL6634 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL5158351 | 0.74 | SMN1; SMN2 (0.51) | — | |
| Hydrochloric Acid SCHEMBL5162319 | 0.73 | SMN1; SMN2 (0.50) | CHRNB2CHRNA4 | |
| SCHEMBL25330280 | 0.72 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL30608680 | 0.72 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL25330282 | 0.72 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL188578 | 0.72 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL5159105 | 0.72 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068186-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | Targacept, Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051216-A2 | 3-PYRIDYLOXYALKYLAMINE OR ARYLOXYALKYLAMINE DERIVATIVES AS CHOLINERGIC AGONISTS | R.J. REYNOLDS TOBACCO COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |