Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751458 | 1.00 | S1PR4 (0.37) | S1PR4S1PR1S1PR3S1PR5TLR9 | |
| SCHEMBL7752639 | 0.90 | RARB (0.38) | S1PR4S1PR1S1PR3S1PR5TLR9 | |
| SCHEMBL7752643 | 0.90 | RARB (0.38) | S1PR4S1PR1S1PR3S1PR5TLR9 | |
| SCHEMBL7750065 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A | |
| SCHEMBL7751456 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A | |
| SCHEMBL7750056 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A | |
| SCHEMBL7748003 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A | |
| SCHEMBL7751404 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A | |
| SCHEMBL7751452 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A | |
| SCHEMBL7751442 | 0.87 | NPC1 (0.43) | PTGESTHRATHRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |