Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752639 | 1.00 | RARB (0.38) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8024694 | 0.90 | RARB (0.46) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7751458 | 0.90 | S1PR4 (0.37) | RAB9ASMN1; SMN2KDM4EHSD17B10TDP1 | |
| SCHEMBL7751463 | 0.90 | S1PR4 (0.37) | RAB9ASMN1; SMN2KDM4EHSD17B10TDP1 | |
| SCHEMBL7751437 | 0.88 | RARB (0.42) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7750464 | 0.88 | RARB (0.42) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7749998 | 0.88 | RARB (0.42) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7751441 | 0.86 | RARB (0.43) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7751372 | 0.86 | RARB (0.43) | RARBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7751365 | 0.86 | RARB (0.43) | RARBRAB9AMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |