Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARG | P13631 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 5/20 | 0.34 |
| ▸ | RXRG | P48443 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751787 | 0.81 | RXRA (0.51) | RXRARARBRARGRARARXRB | |
| SCHEMBL7751790 | 0.81 | RXRA (0.51) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755858 | 0.81 | RARB (0.53) | RXRARARBRARGRARARXRB | |
| SCHEMBL7755860 | 0.81 | RARB (0.53) | RXRARARBRARGRARARXRB | |
| SCHEMBL7751761 | 0.80 | RARB (0.38) | RXRARARBRARGRARARXRB | |
| SCHEMBL7756274 | 0.78 | RARB (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL7756278 | 0.78 | RARB (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL7756281 | 0.73 | RARB (0.40) | RXRARARBRARGRARARXRB | |
| SCHEMBL7786511 | 0.72 | RXRA (0.48) | RXRARARBRARGRARARXRB | |
| SCHEMBL7786513 | 0.72 | RXRA (0.48) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077919-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058486-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | claimed |