SCHEMBL7751806

SCHEMBL7751806

C[N+](C)(C)Cc1cccc2cc(O)ccc12

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.47
TLR8 Q9NR97 1/20 0.42
CHRNB2 P17787 2/20 0.41
CHRNA7 P36544 2/20 0.41
CHRNA4 P43681 2/20 0.41
CYP1A2 P05177 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7646265 0.98 IDH1 (0.46) IDH1TLR8CHRNB2CHRNA7CHRNA4
SCHEMBL30727531 0.80 IDH1 (0.54) IDH1TLR8CYP1A2MTNR1AMTNR1B
SCHEMBL3952728 0.80 IDH1 (0.54) IDH1TLR8CYP1A2MTNR1AMTNR1B
SCHEMBL29418808 0.80 IDH1 (0.54) IDH1TLR8CYP1A2MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL30520083 0.79 IDH1 (0.52) IDH1TLR8CYP1A2MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL30520291 0.79 IDH1 (0.52) IDH1TLR8CYP1A2MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL29678754 0.79 IDH1 (0.52) IDH1TLR8CYP1A2MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL10754555 0.78 PLAU (0.47) CYP1A2CHRM2CHRM1
SCHEMBL7919050 0.77 CYP2D6 (0.59) CYP1A2CHRM2CHRM1
SCHEMBL5539606 0.77 IDH1 (0.48) IDH1TLR8CYP1A2MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066021-A1 NAPHTHALENE CATIONIC COUPLER FOR OXIDATION DYEING OF KERATIN FIBER L'OREAL (FR) 2001-01-10 EP claimed
WO-2000042980-A1 NAPHTHALENE CATIONIC COUPLER FOR OXIDATION DYEING OF KERATIN FIBER L'OREAL (FR) 2000-07-27 WO claimed
EP-1066021-A1 NAPHTHALENE CATIONIC COUPLER FOR OXIDATION DYEING OF KERATIN FIBER L'OREAL (FR) 2001-01-10 EP disclosed
WO-2000042980-A1 NAPHTHALENE CATIONIC COUPLER FOR OXIDATION DYEING OF KERATIN FIBER L'OREAL (FR) 2000-07-27 WO disclosed