Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19733114 | 0.93 | — | — | |
| SCHEMBL703265 | 0.83 | — | — | |
| SCHEMBL6651480 | 0.83 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL1116598 | 0.82 | CA12 (0.31) | KDM5ACA12CA1CA9HTR1B | |
| SCHEMBL22534490 | 0.80 | — | — | |
| SCHEMBL3138589 | 0.79 | ALDH1A1 (0.39) | CYP1A2CYP2D6 | |
| SCHEMBL2119923 | 0.78 | TSHR (0.42) | LMNA | |
| SCHEMBL1614337 | 0.78 | TSHR (0.42) | LMNA | |
| SCHEMBL1389230 | 0.78 | TSHR (0.42) | LMNA | |
| SCHEMBL13864683 | 0.78 | TSHR (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829037-B1 | POWDER COMPOSITIONS SUITABLE FOR A TONER | COATES BROTHERS PLC (GB) | 2001-01-03 | — | — | EP | disclosed |
| US-6045960-A | THE SYNTHETIC THERMOPLASTIC RESIN PARTICLES ARE SURFACE COATED WITH A BLEND OF THE PRIMARY AND SECONDARY REFRACTORY METAL OXIDES AND THE POWDER LUBRICANT | COATES BROTHERS PLC (GB) | 2000-04-04 | — | — | US | disclosed |
| EP-0829037-A1 | POWDER COMPOSITIONS SUITABLE FOR A TONER | Coates Brothers PLC (GB) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038768-A1 | POWDER COMPOSITIONS SUITABLE FOR A TONER | COATES BROTHERS PLC (GB) | 1996-12-05 | — | — | WO | disclosed |