Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980726 | 0.87 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL19002198 | 0.85 | KMT2A (0.53) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL27846661 | 0.83 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL2288515 | 0.81 | KMT2A (0.56) | KMT2AESR1ESR2MEN1GPR88 | |
| SCHEMBL12158259 | 0.81 | TSHR (0.49) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL9066698 | 0.81 | CYP2C19 (0.42) | TSHRL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL1533272 | 0.81 | KMT2A (0.51) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL1094245 | 0.80 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL5257603 | 0.80 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL13684889 | 0.80 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001261645-A | (3S)-3-METHOXYCARBONYL-4-PHENYLBUTYRYL CHLORIDE AND METHOD FOR USING THE SAME | KISSEI PHARMACEUT CO LTD | 2001-09-26 | — | — | JP | disclosed |