Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908467 | 0.82 | CYP2C19 (0.43) | CYP2C19EPHX1CYP2D6SRCCNR1 | |
| SCHEMBL4618760 | 0.82 | MTNR1A (0.48) | CYP2D6SRCCNR1CNR2MTNR1A | |
| SCHEMBL7751977 | 0.81 | KMT2A (0.51) | LMNAALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL971454 | 0.81 | CYP2C19 (0.48) | CYP2C19EPHX1CYP2D6LMNAHSD17B10 | |
| SCHEMBL9357138 | 0.80 | ALDH1A1 (0.37) | CYP2C19EPHX1SRCCNR1CNR2 | |
| SCHEMBL13658246 | 0.79 | POLB (0.50) | CYP2C19EPHX1LMNAHSD17B10KCNQ2 | |
| SCHEMBL19612626 | 0.78 | POLB (0.50) | CNR2LMNAHSD17B10KCNQ2ALDH1A1 | |
| SCHEMBL7255213 | 0.78 | CYP2C19 (0.46) | CYP2C19EPHX1CYP2D6SRCLMNA | |
| SCHEMBL5743275 | 0.77 | RIPK1 (0.48) | ALDH1A1 | |
| SCHEMBL8423195 | 0.77 | RIPK1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540108-B1 | Catalyst composition | SHELL INT RESEARCH (NL) | 1996-01-03 | — | — | EP | disclosed |
| US-5279999-A | Catalyst composition | SHELL OIL COMPANY (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0540108-A1 | Catalyst composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-05-05 | — | — | EP | disclosed |