SCHEMBL7752079

SCHEMBL7752079

O=[N+]([O-])c1ccc(CN2CCCNCCNCCCNCC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 9/20 0.72
HRH3 Q9Y5N1 2/20 0.72
CCR2 P41597 2/20 0.72
MEN1 O00255 1/20 0.72
CHRM2 P08172 1/20 0.72
CHRM1 P11229 1/20 0.72
ADRA2C P18825 1/20 0.72
CXCL12 P48061 1/20 0.72
BLM P54132 1/20 0.72
KMT2A Q03164 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
KCNJ1 P48048 2/20 0.62
KCNH2 Q12809 1/20 0.62
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.56
LMNA P02545 1/20 0.56
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
KHK P50053 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9621043 0.97 CXCR4 (0.67) CXCR4HRH3CCR2MEN1CHRM2
SCHEMBL4021524 0.96 CXCR4 (0.65) CXCR4HRH3CCR2MEN1CHRM2
SCHEMBL5334337 0.93 KCNJ1 (0.70) CXCR4HRH3CCR2MEN1CHRM2
SCHEMBL626660 0.91 KCNJ1 (0.72) CXCR4HRH3CCR2MEN1CHRM2
Bromide SCHEMBL9067030 0.90 KCNJ1 (0.70) CXCR4HRH3CCR2MEN1CHRM2
Hydrochloric Acid SCHEMBL6289818 0.90 KCNJ1 (0.70) CXCR4HRH3CCR2MEN1CHRM2
Hydrochloric Acid SCHEMBL4478110 0.90 KCNJ1 (0.70) CXCR4HRH3CCR2MEN1CHRM2
SCHEMBL14478357 0.86 KCNJ1 (0.84) CXCR4HRH3CCR2MEN1CHRM2
SCHEMBL673078 0.86 CXCR4 (0.59) CXCR4HRH3CCR2MEN1CHRM2
SCHEMBL29490414 0.85 CXCR4 (1.00) CXCR4HRH3CCR2MEN1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001046202-A1 POLYAZACYCLOALKANES, ORGANOMETALLIC COMPLEXES THAT INCORPORATE THEM AS LIGANDS AND THE USE OF SAID COMPOUNDS IN THE EXTRACTION OF HEAVY METALS L'AIR LIQUIDE SOCIETE ANONYME A DIRECTOIRE ET CONSEIL DE SURVEILLANCE POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2001-06-28 WO disclosed
EP-0315188-A2 Methods and materials for the preparation of metal labelled antibody solutions ABBOTT LABORATORIES (US) 1989-05-10 EP disclosed