Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.58 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626660 | 0.98 | KCNJ1 (0.72) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| Bromide SCHEMBL9067030 | 0.97 | KCNJ1 (0.70) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4478110 | 0.97 | KCNJ1 (0.70) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6289818 | 0.97 | KCNJ1 (0.70) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL7752079 | 0.93 | CXCR4 (0.72) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL9621043 | 0.92 | CXCR4 (0.67) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL17805273 | 0.91 | KCNJ1 (0.68) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL4021524 | 0.88 | CXCR4 (0.65) | KCNJ1KCNH2KDM4EALDH1A1LMNA | |
| SCHEMBL9015442 | 0.84 | KCNJ1 (0.97) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL8554661 | 0.84 | KCNJ1 (0.97) | KCNJ1KCNH2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-06-14 | — | — | US | disclosed |
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-09-16 | — | — | US | disclosed |
| US-7312327-B2 | Method of preparing nitrogen macrocycles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2007-12-25 | — | — | US | disclosed |
| US-20040206940-A1 | Novel method of preparing nitrogen macrocycles | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2004-10-21 | — | — | US | disclosed |
| EP-1430036-A1 | NOVEL METHOD OF PREPARING NITROGEN MACROCYCLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003029228-A1 | NOVEL METHOD OF PREPARING NITROGEN MACROCYCLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2003-04-10 | — | — | WO | disclosed |
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0374929-B1 | Process for preparing mono-N-alkylated polyazamacrocycles | DOW CHEMICAL CO (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5652361-A | ANTITUMOR | THE DOW CHEMICAL COMPANY (US) | 1997-07-29 | — | — | US | disclosed |
| EP-0296522-B1 | Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation | DOW CHEMICAL CO (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0353450-B1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | DOW CHEMICAL CO (US) | 1995-03-29 | — | — | EP | disclosed |
| US-5284644-A | Anticancer agent; therapy and diagnosis | DOW CHEMICAL COMPANY, THE | 1994-02-08 | — | — | US | disclosed |
| US-5064956-A | Process for preparing mono-n-alkylated polyazamacrocycles | THE DOW CHEMICAL COMPANY (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0420942-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4994560-A | Radiotherapy, diagnosis | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| WO-1990007261-A2 | PROCESS FOR PREPARING MONO-N-ALKYLATED POLYAZAMACROCYCLES | THE DOW CHEMICAL COMPANY (US) | 1990-07-12 | — | — | WO | disclosed |
| EP-0374929-A1 | Process for preparing mono-n-alkylated polyazamacrocycles | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0353450-A1 | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates | THE DOW CHEMICAL COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989012631-A1 | MACROCYCLIC BIFUNCTIONAL CHELANTS, COMPLEXES THEREOF AND THEIR ANTIBODY CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-28 | — | — | WO | disclosed |
| EP-0296522-A2 | Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation | THE DOW CHEMICAL COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | DCTN3, DCTN1, CDK3 | KCNJ1 3504/4885KCNH2 2087/4885KDM4E 1610/4885 |
| US-20210283278-A1 | CHIRAL CYCLEN COMPOUNDS AND THEIR USES | DCTN3, DCTN1, CDK3 | KCNJ1 3504/4885KCNH2 2087/4885KDM4E 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.