Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752992 | 0.92 | CCKAR (0.65) | CCKARCCKBR | |
| SCHEMBL8519223 | 0.91 | CCKAR (0.58) | CCKARCCKBR | |
| SCHEMBL7751752 | 0.89 | CCKAR (0.70) | CCKARCCKBR | |
| SCHEMBL8405638 | 0.89 | CCKAR (0.55) | CCKARCCKBR | |
| SCHEMBL8406809 | 0.87 | CCKAR (0.54) | CCKARCCKBR | |
| SCHEMBL8806380 | 0.86 | CCKAR (0.71) | CCKARCCKBR | |
| SCHEMBL8405715 | 0.82 | CCKAR (0.51) | CCKARCCKBR | |
| SCHEMBL8804820 | 0.82 | CCKAR (0.66) | CCKARCCKBR | |
| SCHEMBL8803760 | 0.81 | CCKAR (0.62) | CCKARCCKBR | |
| SCHEMBL8804640 | 0.81 | CCKAR (0.85) | CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785794-B1 | ENTERIC COATED COMPOSITIONS OF 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC OR AGONISTIC ACTIVITY | GLAXO WELLCOME INC (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-0785787-B1 | USE OF 1,5-BENZODIAZEPINE DERIVATIVES FOR THE CONTROL OF GASTRIC EMPTYING IN PATIENTS WITH NON-INSULIN DEPENDENT DIABETES MELLITUS | GLAXO WELLCOME INC (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0694039-B1 | 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC AND OR AGONISTIC ACTIVITY | GLAXO WELLCOME INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-0785787-A1 | USE OF 1,5-BENZODIAZEPINE DERIVATIVES FOR THE CONTROL OF GASTRIC EMPTYING IN PATIENTS WITH NON-INSULIN DEPENDENT DIABETES MELLITUS | GLAXO WELLCOME INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5646140-A | CHOLECYSTOKININ ANTAGONIST; APETITE CONTROL | GLAXO WELLCOME INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1996011691-A1 | USE OF 1,5-BENZODIAZEPINE DERIVATIVES FOR THE CONTROL OF GASTRIC EMPTYING IN PATIENTS WITH NON-INSULIN DEPENDENT DIABETES MELLITUS | GLAXO WELLCOME INC. (US) | 1996-04-25 | — | — | WO | disclosed |
| WO-1994024149-A1 | 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC OR AGONISTIC ACTIVITY | GLAXO INC. (US) | 1994-10-27 | — | — | WO | disclosed |