Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 17/20 | 0.65 |
| ▸ | CCKBR | P32239 | 17/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752163 | 0.92 | CCKAR (0.68) | CCKARCCKBR | |
| SCHEMBL7550570 | 0.87 | CCKAR (0.67) | CCKARCCKBRALDH1A1 | |
| SCHEMBL8519223 | 0.82 | CCKAR (0.58) | CCKARCCKBR | |
| SCHEMBL8806407 | 0.81 | CCKAR (0.79) | CCKARCCKBR | |
| SCHEMBL8804000 | 0.81 | CCKAR (0.69) | CCKARCCKBR | |
| SCHEMBL8405638 | 0.80 | CCKAR (0.55) | CCKARCCKBR | |
| SCHEMBL7751752 | 0.79 | CCKAR (0.70) | CCKARCCKBR | |
| SCHEMBL8809199 | 0.79 | CCKAR (0.66) | CCKARCCKBR | |
| SCHEMBL7747691 | 0.79 | CCKBR (1.00) | CCKARCCKBR | |
| SCHEMBL8807834 | 0.78 | CCKAR (0.58) | CCKARCCKBRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694039-B1 | 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC AND OR AGONISTIC ACTIVITY | GLAXO WELLCOME INC (US) | 2001-01-24 | — | — | EP | disclosed |
| US-5646140-A | CHOLECYSTOKININ ANTAGONIST; APETITE CONTROL | GLAXO WELLCOME INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1994024149-A1 | 1,5-BENZODIAZEPINE DERIVATIVES HAVING CCK ANTAGONISTIC OR AGONISTIC ACTIVITY | GLAXO INC. (US) | 1994-10-27 | — | — | WO | disclosed |