SCHEMBL7752209

SCHEMBL7752209

CCCCCCCCCCCCCCCCC(=O)C(=O)OCC

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.79
CES2 O00748 4/20 0.62
CES1 P23141 4/20 0.62
DGKA P23743 1/20 0.52
PPARG P37231 6/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
GPR84 Q9NQS5 5/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 4/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
PTPN1 P18031 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
ALOX15 P16050 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480610 1.00 FAAH (0.79) FAAHCES2CES1DGKAPPARG
SCHEMBL1088961 1.00 FAAH (0.79) FAAHCES2CES1DGKAPPARG
SCHEMBL7640125 1.00 FAAH (0.79) FAAHCES2CES1DGKAPPARG
SCHEMBL7751187 1.00 FAAH (0.79) FAAHCES2CES1DGKAPPARG
SCHEMBL3014656 0.98 FAAH (0.76) FAAHCES2CES1DGKAPPARG
SCHEMBL10704882 0.93 FAAH (0.69) FAAHCES2CES1DGKATSHR
SCHEMBL910019 0.91 FAAH (0.67) FAAHCES2CES1DGKAALDH1A1
SCHEMBL27518866 0.89 FAAH (1.00) FAAHPPARGPPARDPPARAFABP4
SCHEMBL21874390 0.88 FAAH (0.64) FAAHCES2CES1DGKAPPARG
SCHEMBL18101453 0.86 FAAH (0.60) FAAHCES2CES1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001035939-A2 OLEAMIDE IN EPILEPSY UNIVERSITY OF SUNDERLAND (GB) 2001-05-25 WO claimed
US-10882246-B2 Three-dimensional shaped article and method for producing three-dimensional shaped article FUJI XEROX CO., LTD. (JP) 2021-01-05 US disclosed
US-20190111613-A1 THREE-DIMENSIONAL SHAPED ARTICLE AND METHOD FOR PRODUCING THREE-DIMENSIONAL SHAPED ARTICLE FUJI XEROX CO., LTD. (JP) 2019-04-18 US disclosed
WO-2001035939-A2 OLEAMIDE IN EPILEPSY UNIVERSITY OF SUNDERLAND (GB) 2001-05-25 WO disclosed
US-6096784-A Inhibitors of oleamide hydrolase THE SCRIPPS RESEARCH INSTITUTE (US) 2000-08-01 US disclosed
EP-0910561-A4 INHIBITORS OF OLEAMIDE HYDROLASE SCRIPPS RESEARCH INST (US) 2000-06-07 EP disclosed
EP-0910561-A1 INHIBITORS OF OLEAMIDE HYDROLASE The Scripps Research Institute (US) 1999-04-28 EP disclosed
US-5856537-A Inhibitors of oleamide hydrolase THE SCRIPPS RESEARCH INSTITUTE (US) 1999-01-05 US disclosed
WO-1997049667-A1 INHIBITORS OF OLEAMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 1997-12-31 WO disclosed
US-5208223-A Enzyme inhibitors AMERICAN CYANAMID COMPANY (US) 1993-05-04 US disclosed
US-5144045-A Treatment of inflammatory related disorders AMERICAN CYANAMID COMPANY (US) 1992-09-01 US disclosed