Methyl Alcohol

Methyl Alcohol

SCHEMBL7752255

CC1(C)CCC(C)(C)c2cc(CC#Cc3ccccc3)ccc21.CO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP26A1 O43174 7/20 0.48
RXRA P19793 6/20 0.48
RARB P10826 5/20 0.48
RARG P13631 5/20 0.48
RARA P10276 4/20 0.48
RXRB P28702 3/20 0.48
CYP3A4 P08684 3/20 0.48
RXRG P48443 2/20 0.48
CRABP2 P29373 1/20 0.48
CYP26B1 Q9NR63 7/20 0.46
PPARG P37231 2/20 0.42
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7751241 0.86 CYP26A1 (0.48) CYP26A1RXRARARBRARGRARA
SCHEMBL7746076 0.86 CYP26A1 (0.48) CYP26A1RXRARARBRARGRARA
SCHEMBL7746459 0.84 CYP26A1 (0.46) CYP26A1RXRARARBRARGRARA
SCHEMBL6372002 0.84 RARB (0.71) CYP26A1RXRARARBRARGRARA
SCHEMBL7752077 0.80 RARB (0.55) CYP26A1RXRARARBRARGRARA
SCHEMBL7928437 0.80 RARB (0.55) CYP26A1RXRARARBRARGRARA
SCHEMBL7751953 0.80 RARB (0.45) CYP26A1RXRARARBRARGRARA
SCHEMBL7936963 0.79 RXRA (0.41) CYP26A1RXRARARBRARGRARA
SCHEMBL7746406 0.78 CYP26A1 (0.53) CYP26A1RXRARARBRARGRARA
SCHEMBL7746475 0.77 RARG (0.55) CYP26A1RXRARARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832057-B1 DIAROMATIC PROPYNYL OR DIENYL COMPOUNDS CT INTERNAT DE (FR) 2001-01-03 EP claimed