Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.52 |
| ▸ | ITGAV | P06756 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753614 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL7752535 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL27547990 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL7753667 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL7753368 | 0.86 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL27489722 | 0.86 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL7752655 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL7753251 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL7753569 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL7748703 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |