Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747800 | 0.89 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2KDM4EHIF1AMAPT | |
| SCHEMBL7751834 | 0.89 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2KDM4EHIF1AMAPT | |
| SCHEMBL8504220 | 0.74 | HIF1A (0.45) | ALDH1A1KDM4EHIF1ALMNARAB9A | |
| SCHEMBL14877479 | 0.68 | HIF1A (0.42) | ALDH1A1HIF1ALMNAHTT | |
| SCHEMBL8846269 | 0.67 | NPC1 (0.41) | ALDH1A1SMN1; SMN2KDM4EHIF1AL3MBTL1 | |
| SCHEMBL8846279 | 0.67 | NPC1 (0.41) | ALDH1A1SMN1; SMN2KDM4EHIF1AL3MBTL1 | |
| SCHEMBL8761028 | 0.66 | SIRT2 (0.38) | ALDH1A1KDM4EHIF1AMAPTF2 | |
| SCHEMBL23972111 | 0.66 | KMT2A (0.37) | ALDH1A1SMN1; SMN2KDM4EHIF1AMAPT | |
| SCHEMBL7741705 | 0.66 | HIF1A (0.39) | HIF1A | |
| SCHEMBL13148667 | 0.66 | HIF1A (0.46) | ALDH1A1HIF1AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070052-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051579-A1 | FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP | AVENTIS CROPSCIENCE S.A. (FR) | 1999-10-14 | — | — | WO | disclosed |