SCHEMBL7752886

SCHEMBL7752886

Nc1cc(N)c2cc(N)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 3/20 0.48
CYP3A4 P08684 3/20 0.48
CASP1 P29466 3/20 0.46
CASP7 P55210 2/20 0.46
HBB P68871 2/20 0.46
HIF1A Q16665 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
PLAU P00749 2/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
LMNA P02545 3/20 0.41
HTT P42858 2/20 0.41
F2 P00734 1/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31722811 1.00 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL21409802 0.93 PLAU (0.44) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL29463756 0.82 PLAU (0.45) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL678473 0.82 PLAU (0.45) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL29389942 0.82 PLAU (0.45) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL17323165 0.79 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL2445157 0.78 ALDH1A1 (0.57) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL21499706 0.78 HPRT1 (0.43) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL14742694 0.77 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP3A4CASP1CASP7
SCHEMBL5514092 0.76 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP3A4CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
CN-111886278-A Triazine ring-containing polymer, resin composition, cured film, and solid-state imaging element 东丽株式会社 2020-11-03 CN disclosed
US-10793584-B2 Naphthobischalcogenadiazole derivative and production method therefor OSAKA UNIVERSITY (JP) 2020-10-06 US disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
EP-0182919-B1 THERMOSETTING RESIN COMPOSITION MITSUI PETROCHEMICAL IND (JP) 1994-12-28 EP disclosed
EP-0526490-B1 TEMPERATURE AND SOLVENT-RESISTANT INK FOR THE INK-JET PRINTING PROCESS BECK & CO AG DR (DE) 1994-07-20 EP disclosed
EP-0310424-B1 Thermosetting resin composition MITSUI PETROCHEMICAL IND (JP) 1994-01-05 EP disclosed
US-4012361-A Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine RHONE-POULENC S.A. (FR) 1977-03-15 US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed
US-3998904-A POLYAMINES WITH IMIDE GROUPS RHONE-POULENC S.A. (FR) 1976-12-21 US disclosed
US-3978152-A HEAT-RESISTANT RESINS DERIVED FROM A BIS-IMIDE, AN EPOXY RESIN AND A POLYAMINE RHONE-POULENC INDUSTRIES (FR) 1976-08-31 US disclosed
US-3970714-A Heat-stable polyimide resin modified by unsaturated polyester RHONE-POULENC S.A. (FR) 1976-07-20 US disclosed
US-3966678-A Maleic anhydride-polyaldimine prepolymers RHONE-POULENC S.A. (FR) 1976-06-29 US disclosed
US-3950279-A DI- OR TRI-MALEIMIDE, AZOMETHINE, SOLID FOAMING AGENT CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3947385-A Mixtures containing prepolymers, which can be converted to heat-resistant foamed plastics CIBA-GEIGY CORPORATION (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793584-B2 Naphthobischalcogenadiazole derivative and production method therefor CYP24A1, CYP26B1, CYP21A2 ALDH1A1 600/4885HSD17B10 947/4885CYP3A4 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.